GW-501516 (Cardarine), (10mg/capsule) 60 Capsules
Original price was: $95.95.$69.95Current price is: $69.95.
GW-501516 (Cardarine) is a synthetic agonist of peroxisome proliferator-activated receptor delta (PPARδ), a ligand-activated nuclear receptor that regulates transcriptional activity through interaction with specific DNA response elements. High-affinity binding to PPARδ induces receptor conformational changes that… CAS: 317318-70-0 | Formula: C21H18F3NO3S2 | Content: 600 mg (10 mg per capsule) | Research use only | Third-party lab tested.
Buy GW-501516 (Cardarine), (10mg/capsule) 60 Capsules – Swiss Chems USA
GW-501516 (Cardarine), (10mg/capsule) 60 Capsules — Research Overview
GW-501516 (Cardarine) is a synthetic agonist of peroxisome proliferator-activated receptor delta (PPARδ), a ligand-activated nuclear receptor that regulates transcriptional activity through interaction with specific DNA response elements. High-affinity binding to PPARδ induces receptor conformational changes that promote co-regulator recruitment, transcriptional complex formation, and downstream gene expression modulation. Research applications include PPARδ pharmacology, nuclear receptor signaling, transcriptional regulation, ligand-receptor interaction studies, structure-activity relationship investigations, and comparative analyses of PPAR family agonists.
Also in our SARMs range: S4 (Andarine) at 25mg/capsule and RAD-140 (Testolone) at 10mg/capsule. Available in multi-item packs: S4 + GW-501516 Stack and S4 + S23 + GW-501516 Value Pack.
- High Purity – 99% Purity Guaranteed
- Independently Lab Tested
- Research Grade Quality
- For Laboratory Research Use Only
Intended use: This material is supplied for laboratory and in-vitro research only. It is not a drug, food, or cosmetic and is not intended for human or animal consumption.
GW-501516 (Cardarine), (10mg/capsule) 60 Capsules Chemical Properties
| Property | Specification |
|---|---|
| Chemical Formula | C21H18F3NO3S2 |
| Synonyms | Endurobol, GW501516, GW 501516, GW-501516, 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]acetic acid |
| Molar Mass | 453.50 g/mol |
| CAS Number | 317318-70-0 |
| PubChem CID | 9803963 |
| Total Compound Content | 600 mg (10 mg per capsule) |
GW-501516 (Cardarine), (10mg/capsule) 60 Capsules Research Applications
GW-501516 is a thiazole-class agonist of peroxisome proliferator-activated receptor delta (PPARδ), a ligand-activated nuclear receptor that regulates transcription through heterodimerization with retinoid X receptor (RXR). Upon receptor activation, PPARδ undergoes conformational changes that facilitate co-regulator recruitment, transcriptional complex assembly, and modulation of downstream gene expression. Experimental investigations have examined the influence of GW-501516 on transcriptional networks associated with mitochondrial function, substrate utilization pathways, and nuclear receptor signaling. Its well-characterized pharmacological profile and high receptor selectivity have established GW-501516 as a widely used reference compound in PPARδ pharmacology, transcriptional regulation studies, ligand-receptor interaction research, and structure-activity relationship investigations. Supplied in 10 mg capsules. Independently third-party HPLC-tested; COA available per batch.
GW-501516 (Cardarine), (10mg/capsule) 60 Capsules Lab Results & Certificates of Analysis
Third-party analytical reports associated with this research compound:
- GW-501516 (HPLC) — September 12, 2026 | Verification
- GW-501516 (HPLC) — September 12, 2026 | Verification
- GW-501516 (HPLC) — September 12, 2026 | Verification
- GW-501516 (Heavy Metal) — June 19, 2026 | Verification
- GW-501516 (GC-MS/LC-MS Contamination Screening) — June 17, 2026 | Verification
GW-501516 (Cardarine), (10mg/capsule) 60 Capsules Frequently Asked Questions
How does GW-501516’s PPARδ selectivity differ from PPARα and PPARγ agonists?
GW-501516 exhibits high selectivity for PPARδ relative to other members of the peroxisome proliferator-activated receptor family. This selectivity enables investigation of PPARδ-dependent transcriptional activity without the confounding receptor interactions associated with PPARα or PPARγ agonists. As a result, GW-501516 is frequently utilized in studies examining receptor subtype specificity, co-regulator recruitment, and ligand-dependent nuclear receptor signaling.
What is the mechanism of action of GW-501516 at the PPARδ receptor?
GW-501516 binds PPARδ with high affinity, promoting receptor activation, heterodimerization with retinoid X receptor (RXR), and recruitment of transcriptional co-regulators. This process facilitates transcriptional complex assembly and modulation of downstream gene expression. These characteristics make GW-501516 a valuable tool for investigating PPARδ signaling mechanisms, transcriptional regulation, and ligand-receptor interactions.
Why is GW-501516 commonly used as a reference compound in PPARδ research?
A: GW-501516 possesses a well-characterized pharmacological profile, high receptor selectivity, and extensive documentation within the scientific literature. These properties have established it as a widely used reference compound for studies involving PPARδ pharmacology, nuclear receptor signaling, transcriptional pathway characterization, structure-activity relationships, and comparative investigations of PPAR family agonists.
Research Use Disclaimer
All product information is provided for educational and laboratory research reference only. Any form of introduction into humans or animals is prohibited. Handle only in licensed research settings in accordance with applicable laws and institutional protocols.
| Weight | 3 lbs |
|---|
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