HCG 5000 IU — Research Overview

Human chorionic gonadotropin (hCG) is a heterodimeric glycoprotein produced by trophoblastic tissue during early embryogenesis. The α-subunit is structurally homologous to those of LH, FSH, and TSH; the unique β-subunit confers selective high-affinity binding to LHCGR. LHCGR engagement activates Gsα-coupled adenylyl cyclase, driving cAMP accumulation and PKA-mediated phosphorylation of downstream steroidogenic targets including CYP11A1, CYP17A1, and 3β-HSD. In preclinical cell-based models, hCG is used to interrogate Leydig cell responsiveness, CYP enzyme induction kinetics, and receptor desensitisation and internalisation dynamics. The prolonged plasma half-life of hCG relative to LH — attributable to the heavily sialylated β-subunit — makes it a preferred tool for studying sustained LHCGR stimulation versus pulsatile LH receptor engagement in experimental steroidogenesis models. Supplied as freeze-dried lyophilised preparation. Independently third-party HPLC-tested; COA available per batch.

Also available: HMG 75 IU. Reconstitution supplies: Bacteriostatic Water and Sterile Water. Related capsule compounds include Enclomiphene at 12.5mg/capsule.

• High Purity – 99% Purity Guaranteed
• Independently Lab Tested
• Research Grade Quality
• For Laboratory Research Use Only

Intended use: This material is supplied for laboratory and in-vitro research only. It is not a drug, food, or cosmetic and is not intended for human or animal consumption.

HCG 5000 IU Chemical Properties

HCG 5000 IU Research Applications

Human chorionic gonadotropin (hCG) is a heterodimeric glycoprotein produced by trophoblastic tissue during early embryogenesis. The α-subunit is structurally homologous to those of LH, FSH, and TSH; the unique β-subunit confers selective high-affinity binding to LHCGR. LHCGR engagement activates Gsα-coupled adenylyl cyclase, driving cAMP accumulation and PKA-mediated phosphorylation of downstream steroidogenic targets including CYP11A1, CYP17A1, and 3β-HSD. In preclinical cell-based models, hCG is used to interrogate Leydig cell responsiveness, CYP enzyme induction kinetics, and receptor desensitisation and internalisation dynamics. The prolonged plasma half-life of hCG relative to LH — attributable to the heavily sialylated β-subunit — makes it a preferred tool for studying sustained LHCGR stimulation versus pulsatile LH receptor engagement in experimental steroidogenesis models. Supplied as freeze-dried lyophilised preparation. Independently third-party HPLC-tested; COA available per batch.

HCG 5000 IU Lab Results & Certificates of Analysis

Third-party analytical reports associated with this research compound:

• HCG (HPLC) — June 18, 2026 | Verification

HCG 5000 IU Frequently Asked Questions

Research Use Disclaimer

All product information is provided for educational and laboratory research reference only. Any form of introduction into humans or animals is prohibited. Handle only in licensed research settings in accordance with applicable laws and institutional protocols.