PT-141 (Bremenalotide), 10mg
Price range: $49.99 through $499.90
PT-141 (Bremelanotide) is a synthetic cyclic lactam peptide and melanocortin receptor agonist that is a likely metabolite of Melanotan II, differing in that it carries a carboxyl group where MT-II carries an amide. It has high affinity for MC3R and MC4R. Research applications include MC3R/MC4R pharmacology,… CAS: 189691-06-3 | Formula: C50H68N14O10 | Content: 10 mg per vial | Research use only | Third-party lab tested.
Buy PT-141 (Bremenalotide), 10mg – Swiss Chems USA
PT-141 (Bremenalotide), 10mg — Research Overview
PT-141 (Bremelanotide) is a synthetic cyclic lactam peptide and melanocortin receptor agonist that is a likely metabolite of Melanotan II, differing in that it carries a carboxyl group where MT-II carries an amide. It has high affinity for MC3R and MC4R. Research applications include MC3R/MC4R pharmacology, melanocortin system central/peripheral signalling, and dopaminergic pathway interaction studies.
- High Purity – 99% Purity Guaranteed
- Independently Lab Tested
- Research Grade Quality
- For Laboratory Research Use Only
Intended use: This material is supplied for laboratory and in-vitro research only. It is not a drug, food, or cosmetic and is not intended for human or animal consumption.
PT-141 (Bremenalotide), 10mg Chemical Properties
| Property | Specification |
|---|---|
| Chemical Formula | C50H68N14O10 |
| Synonyms | Bremelanotide, PT141, Vyleesi (trade name) |
| Molar Mass | 1,025.2 g/mol |
| CAS Number | 189691-06-3 |
| PubChem CID | 9941379 |
| Total Compound Content | 10 mg per vial |
| Shelf Life | 36 months |
PT-141 (Bremenalotide), 10mg Research Applications
PT-141 (Bremelanotide) is a cyclic heptapeptide melanocortin receptor agonist developed as a synthetic analogue of Melanotan II. Its primary structural distinction from Melanotan II is the presence of a carboxyl terminus in place of the corresponding amide group, resulting in differences in receptor interaction characteristics and physicochemical properties. PT-141 exhibits high affinity for melanocortin receptor subtypes MC3R and MC4R and has been extensively investigated as a research tool for melanocortin receptor pharmacology and receptor-mediated signaling mechanisms. Experimental studies have examined the relationship between PT-141 and melanocortin receptor activation, ligand-receptor binding dynamics, receptor subtype selectivity, and downstream signaling pathways associated with MC3R and MC4R activity. Research applications include melanocortin receptor characterization, receptor pharmacology, structure-activity relationship investigations, ligand-receptor interaction studies, and mechanistic evaluation of melanocortin signaling systems. Supplied as a lyophilized preparation (10 mg/vial). Independently third-party HPLC-tested; COA available per batch.
PT-141 (Bremenalotide), 10mg Frequently Asked Questions
What distinguishes PT-141 from other melanocortin receptor agonists?
PT-141 is a cyclic heptapeptide melanocortin receptor agonist characterized by high affinity for MC3R and MC4R receptor subtypes. Its receptor interaction profile differs from other melanocortin ligands through variations in receptor subtype selectivity, binding characteristics, and signaling activity. These properties have established PT-141 as a valuable research tool for investigating melanocortin receptor pharmacology, receptor-mediated signaling mechanisms, and ligand-receptor interactions.
What is the structural difference between PT-141 and Melanotan II?
PT-141 and Melanotan II share a closely related cyclic heptapeptide framework but differ at the C-terminal region of the molecule. PT-141 contains a free carboxyl group, whereas Melanotan II contains a corresponding amide functionality. This structural variation influences physicochemical properties, receptor interaction characteristics, and pharmacological behavior, making the two compounds useful for comparative structure-activity relationship investigations within melanocortin receptor research.
Why is PT-141 useful for MC3R and MC4R research?
PT-141 exhibits strong activity at MC3R and MC4R receptor subtypes and has been extensively utilized in studies examining receptor activation, ligand-binding dynamics, receptor subtype selectivity, and downstream melanocortin signaling pathways. Its well-characterized pharmacological profile makes it a useful research tool for investigations involving melanocortin receptor biology, receptor pharmacology, signal transduction mechanisms, and comparative analyses of melanocortin receptor agonists.
Research Use Disclaimer
All product information is provided for educational and laboratory research reference only. Any form of introduction into humans or animals is prohibited. Handle only in licensed research settings in accordance with applicable laws and institutional protocols.
| Weight | 1 lbs |
|---|---|
| Pt 141 Bremenalotide 10Mg |
1 vial ,KIT (10 vials) |
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